THE DANGER THEORY: TWENTY YEARS LATER

The Danger Theory: Twenty Years Later

The Danger Theory: Twenty Years Later

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The self-nonself theory has dominated immunology since the 1950s.In the 1990s, Matzinger and her colleagues suggested a new, competing theory, called the danger theory.This theory Doll house furniture has provoked mixed acclaim: enthusiasm and criticism.Here we assess the danger theory vis-à-vis recent experimental data on innate immunity, transplantation, cancers and tolerance to foreign entities, and Lubes and Lotions try to elucidate more clearly whether danger is well defined.

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